Clinical Pharmacology,

Edition 12

Editors: Edited by Morris J. Brown, MA MSc FRCP FAHA FBPharmacolS FMedSci, Pankaj Sharma, MD PhD FRCP, Fraz A. Mir, MA, FRCP and Peter N. Bennett, MD FRCP

Publication Date: 21 May 2018

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‘The very last thing a drug regulator wishes to be able to say is, like Lord Byron (1788-1824), on the publication of his poem Childe Harold’s Pilgrimage, ‘I awoke one morning and found myself famous.’

The twelfth edition of this long-established textbook of clinical pharmacology (first published in 1960) continues its fine tradition of balancing science and practice for improved evidence-based drug therapy and good prescribing in therapeutic settings increasingly complicated by intercurrent disease and polypharmacy.

Key Features

Coverage of all major therapeutic topics by body system
Introductory sections give brief chapter synopses
Case studies where relevant
Covers the needs of the developing world with a focus on practical prescribing and health technology assessment
Definition, tips, brief explanation boxes throughout
Interesting histories, etymologies and provenances of terms throughout
Entertaining footnotes throughout

About the author

Edited by Morris J. Brown, MA MSc FRCP FAHA FBPharmacolS FMedSci, Prof of Endocrine Hypertension, William Harvey Institute, Queen Mary University of London, Charterhouse Square, London, UK; Pankaj Sharma, MD PhD FRCP, Professor of Neurology and Director, Institute of Cardiovascular Research, Royal Holloway College, University of London; and Consultant Neurologist, Imperial College Healthcare NHS Trust, London, UK; Fraz A. Mir, MA, FRCP, Consultant Clinical Pharmacologist, Division of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK and Peter N. Bennett, MD FRCP, Formerly Reader in Clinical Pharmacology, University of Bath, and Consultant Physician, Royal United Hospital, Bath, UK

Section 1: General
1 Clinical pharmacology
2 Topics in drug therapy
3 Discovery and development of drugs
4 Evaluation of drugs in humans
5 Health Technology Assessment
6 Regulation of medicines
7 Classification and naming of drugs

Section 2: From Pharmacology to Toxicology
8 General pharmacology
9 Unwanted effects and adverse drug reactions
10 Poisoning, overdose, antidotes
11 Drug dependence

Section 3: Infection and Inflammation
12 Chemotherapy of infections
13 Antibacterial drugs
14 Chemotherapy of bacterial infections
15 Viral, fungal, protozoal and helminthic infections
16 Drugs for inflammation and joint disease
17 Drugs and the skin

Section 4: Nervous System
18 Pain and analgesics
19 Anaesthesia and neuromuscular block
20 Psychotropic drugs
21 Neurological disorders - epilepsy, Parkinson’s disease, and multiple sclerosis

Section 5: Cardiorespiratory and Renal Systems
22 Cholinergic and antimuscarinic (anticholinergic) mechanisms and drugs
23 Adrenergic mechanisms and drugs
24 Arterial hypertension, angina pectoris, myocardial infarction and heart failure
25 Cardiac arrhythmia
26 Hyperlipidaemias
27 Kidney and genitourinary tract
28 Respiratory system

Section 6: Blood and Neoplastic Disease
29 Drugs and haemostasis
30 Cellular disorders and anaemias
31 Neoplastic disease and immunosuppression

Section 7: Gastrointestinal System
32 Oesophagus, stomach and duodenum
33 Intestines
34 Liver, biliary tract, pancreas

Section 8: Endocrine System, Metabolic Conditions
35 Adrenal corticosteroids, antagonists, corticotropin
36 Diabetes mellitus, insulin, oral antidiabetes agents, obesity
37 Thyroid hormones, antithyroid drugs
38 Hypothalamic, pituitary and sex hormones
39 Vitamins, calcium, bone

Title Reviews

"Overall this is an excellent book"

‘Invaluable reference book with a long, tried history. I would a have to say of all the books on this subject in my library (which includes the massive The Pharmacological Basis of Therapeutics), Bennett’s is the most frequently referenced. No surgery or pharmacy department worthy of the name should be without a copy of the book.’

‘Used this book for my prescribing very useful.’

‘This book is the best therapeutics pharmacology text I have come across. It is especially useful for prescribers and medical students as it has all the essentials you need to know about most drugs in use.’

‘This is an excellent pharmacology text book covering all the major therapeutic topics in a pleasantly readable fashion. The book covers many areas, including drug development and the pharmacokinetic aspects of drugs that are relevant to everyday prescribing, benefiting from the input of a great number of practising doctors with their accompanying years of clinical experience. The book contains numerous amusing references, which certainly managed to stimulate my interest in what can easily become a rather dull and complicated subject. I would highly recommend this book to clinical medical students and indeed to anyone in the medical profession.’

ISBN: 9780702073281

Page Count: 720

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