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Book Details
Cann's Principles of Molecular Virology, Seventh Edition provides an easily accessible introduction to modern virology, presenting principles in a clear and concise manner. The new edition provides the history of virology and the fundamentals of the molecular basis of how viruses work. It discusses the interactions which control the structure of virus particles, the ways viruses infect cells, how viruses replicate themselves, and the consequences and pathogenesis of virus infection for host organisms. This fully updated edition also reflects advances made in the field and includes new content on phage therapy, CRISPR as a phage defense / offense system, new ideas about evolution, and giant viruses. With the addition of ancillary resources, Principles of Molecular Virology, Seventh Edition is an essential foundational reference for academics, graduate students, and advance undergraduates in virology, molecular biology, and microbiology as well as researchers entering virology, infectious disease, and immunology research.
Key Features
- Provides a conceptual approach to the principles of molecular virology, with important examples of new advances in virology
- Includes new concepts in this edition include coverage of emerging topics and new technologies in viral research like phage therapy, CRISPR as a phage defense / offense system, new ideas about evolution, and giant viruses
- Contains updated learning outcomes and further reading for each chapter
- Supported by online resources for students and instructors
About the author
By Edward P. Rybicki, Professor, Department of Molecular and Cell Biology and Biopharming Research Unit, University of Cape Town, South AfricaPreface
1. What are viruses, and how were they discovered?
Introduction 
The history of the discovery of viruses 
References 
Recommended Reading 
2. Viruses and their particles
Viruses and their particles 
Virions 
References
Recommended reading 
3. Virus origins and genetics
The structure and complexity of virus genomes 
Origins of viruses 
From what did viruses evolve? 
The origins of modern eukaryote viruses 
Of ERVs and EVEs 
The complexity of virus genomes
Molecular genetics 
Virus genetics 
The global virome 
Epidemiology 
Summary 
References 
Recommended reading 
4. Virus genomes and their replication
Overview of virus replication 
Entrance into cells and viral genome
replication 
Genome replication and gene expression 
Assembly of virions 
Summary 
References 
Recommended reading 
5. Expression of virus genomes
Expression of genetic information 
Virus genome coding strategies 
Transcriptional control of expression 
Posttranscriptional control of expression 
Summary 
References 
Recommended reading 
6. Infection and immunity
Virus infection of prokaryotes 
Virus infections of plants 
Immune responses to virus infections in animals 
Innate immune responses 
Adaptive immune responses in vertebrates 
RNA interference 
Virus-host interactions 
The course of virus infections 
Prevention and therapy of virus infection 
Viruses as therapeutics 
Chemotherapy of virus infections 
Summary 
References 
Recommended reading 
7. Viral pathogenesis
Mechanisms of cellular injury 
Viruses and immunodeficiency 
Acquired immunodeficiency syndrome
(AIDS) 
Virus-related diseases 
Bacteriophages and human disease 
Cell transformation by viruses 
Cell transformation by retroviruses 
Cell transformation by DNA viruses 
Viruses and cancer 
Summary 
References 
Recommended reading 
8. Panics and pandemics
New, emerging, and re-emerging viruses 
Re-emerging viruses 
Plant viruses 
Novel human viruses 
Zoonoses 
Biowarfare and bioterrorism 
Summary 
References 
Recommended reading 
9. Subviral agents: Deltaviruses and prions
Hepatitis delta virus 
Prions 
Molecular biology of prions 
References 
Recommended reading 
Appendix 1 
Index 
 
							







 
                