Gene Therapy: Prospective Technology assessment in its societal context - Edition 1 - Edited by Jörg Niewöhner and Christof Tannert Elsevier Educate

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Gene Therapy: Prospective Technology assessment in its societal context,

Edition 1

Edited by Jörg Niewöhner and Christof Tannert

Publication Date: 21 Jul 2006

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This book presents work that has been conducted as part of the research project "Discourse on ethical questions of biomedicine" of the interdisciplinary Working Group Bioethics and Science Communication at the Max-Delbrueck-Center for Molecular Medicine (MDC)in Berlin-Buch, Germany. This book offers ground-breaking ideas on how the daily interworking of cutting-edge biomedical research assess the broader social context and its communication to stakeholders and the public. Editors cover three aspects: Scientific, Ethical and Legal, and Perception and Communication. This work establishes an international and interdisciplinary network of excellent researchers at the beginning of their careers, who brilliantly integrate their work into the different perspectives on gene therapy from the natural and social sciences, as well as the humanities and law.

Key Features

* Discusses biological and cellular barriers limiting the clinical application of nonviral gene deliverysystems* Addresses such questions as: Does patent granting hinder the development of Gene Therapy products?* Offers insight in the future of public perception of gene therapy in Europe* Provides details on how to communicate risks in gene therapy

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Edited by Jörg Niewöhner, Max-Delbrueck Centre, Berlin, Germany and Christof Tannert

Table of contents
PREFACE
CHAPTER 1. Editorial Building Interdisciplinarity in Research on Gene Therapy
Section I Scientific Aspects
CHAPTER 2. Identification of genes causing autosomal recessive retinitis pigmentosa
CHAPTER 3. Recombinant Adeno-Associated Viral Vectors for CNS Gene Therapy
CHAPTER 4. Controlling Adenoviral Gene Transfer in Heart By Catheter Based Coronary Perfusion
CHAPTER 5. Biological and cellular barriers limiting the clinical application of nonviral gene delivery
systems
CHAPTER 6. Design, Preparation and Characterization of Polymer-Based Nanocarriers for Non-Viral
Gene Delivery
CHAPTER 7. Neurogenetic Imaging
CHAPTER 8. Implications of Fetal Gene Therapy for the Medical Profession
Section II Ethical and Legal Aspects
CHAPTER 9. Ethical Issues in Gene Therapy Research, An American Perspective
CHAPTER 10. Do germline interventions justify the restriction of reproductive autonomy?
CHAPTER 11. Ghost of Christmas Past
Eugenics and other moral dilemmas surrounding genetic interventions: a discussion in
the context of virtue ethics
CHAPTER 12. Biomedical Research and Ethical Regulations in China. Some Observations about gene
Therapy, Human Research, and Struggles of Interest
CHAPTER 13. Does patent granting hinder the development of Gene Therapy products?
CHAPTER 14. On The Political Side of Gene Therapy. What Can Be Drawn from the French Situation?
Section III Perception and Communication
CHAPTER 15. How to Communicate Risks in Gene Therapy?
CHAPTER 16. European analysis of the various procedure existing to interrupt a clinical research protocol
thanks to a French example of gene therapy
CHAPTER 17. The future of public perception of gene therapy in Europe, an educated guess

ISBN: 9780444528063

Page Count: 274

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Kaplitt and During: Gene Therapy of the Central Nervous System: From Bench to Bedside (Dec 2005, ISBN-10/13: 0-12-397632-4/ 978-0-12-397632-1)
Richards and Hawley: The Human Genome, 2e (Oct 2004, ISBN-10/13: 0-12-333462-4/ 978-0-12-333462-6)
Davidson: The Regulatory Genome (May 2006, ISBN-10/13: 0-12-088563-8/ 978-0-12-088563-3)

Practicing scientists, graduate students, academic clinicians who want to understand more about the ethical issues of gene therapy.

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