Clinical Biochemistry: Metabolic and Clinical Aspects,
Edition 3 With Expert Consult accessEditors: By William J. Marshall, MA, PhD, MSc, MBBS, FRCP, FRCPath, FRCPEdin, FRSB, FRSC, Márta Lapsley, MB BCh BAO, MD, FRCPath, Andrew Day, MA MSc MBBS FRCPath and Ruth Ayling, PhD FRCP FRCPath
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Description
Now fully revised and updated, Clinical Biochemistry, third edition is essential reading for specialty trainees, particularly those preparing for postgraduate examinations. It is also an invaluable current reference for all established practitioners, including both medical and scientist clinical biochemists.
Building on the success of previous editions, this leading textbook primarily focuses on clinical aspects of the subject, giving detailed coverage of all conditions where clinical biochemistry is used in diagnosis and management – including nutritional disorders, diabetes, inherited metabolic disease, metabolic bone disease, renal calculi and dyslipidaemias. The acquisition and interpretation of clinical biochemical data are also discussed in detail.
Key Features
- From the author of the popular Clinical Chemistry medical student textbook
- there are many competing texts on clinical chemistry, the vast majority concentrate on the technology; this book concentrates on the clinical
- Ideally suited for preparation for the MRCPath and similar examinations
New Features
- Expanded sections on haematology and immunology for clinical biochemists provide a thorough understanding of both laboratory and clinical aspects
- New chapters are included on important evolving areas such as the metabolic response to stress, forensic aspects of clinical biochemistry and data quality management
- An extended editorial team - including three expert new additions – ensures accuracy of information and relevance to current curricula and clinical practice
- A superb new accompanying electronic version provides an enhanced learning experience and rapid reference anytime, anywhere!
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About the author
By William J. Marshall, MA, PhD, MSc, MBBS, FRCP, FRCPath, FRCPEdin, FRSB, FRSC, Emeritus Reader in Clinical Biochemistry, Kings College London, London, UK; formerly Consultant Clinical Biochemist and Clinical Director of Pathology, The London Clinic, London, UK.; Márta Lapsley, MB BCh BAO, MD, FRCPath, Consultant Chemical Pathologist, Epsom and St. Helier University Hospitals NHS Trust, Epsom, Surrey, UK; Andrew Day, MA MSc MBBS FRCPath, Consultant in Clinical Biochemistry and Metabolic Medicine, University Hospitals Bristol NHS Foundation Trust, Bristol, UK and Ruth Ayling, PhD FRCP FRCPath, Consultant in Clinical Biochemistry, Derriford Hospital, Plymouth, UK
The acquisition of biochemical data
The interpretation of biochemical data
Sodium, water and potassium
Hydrogen ion homoeostasis, tissue oxygenation and their disorders
Calcium, phosphate and magnesium
The kidneys, renal function and renal failure. Proteinuria
Renal tubular disorders and renal stone disease
The clinical biochemistry of nutrition
Nutritional disorders and their management
The clinical biochemistry of the gastrointestinal tract
The assessment of hepatic function and investigation of jaundice
Acute and chronic liver disease
Diabetes mellitus: pathophysiology and biochemical background
The clinical management of diabetes mellitus
Hypoglycaemia
Hypothalamic, pituitary and adrenal disorders
Thyroid dysfunction
Hormonal aspects of non-endocrine disease
Abnormal sexual development
The clinical biochemistry of female reproductive function, including pregnancy, oral contraception and hormone replacement therapy
Reproductive function in the male
Inherited metabolic disease
Paediatric clinical biochemistry
Biochemical aspects of anaemia
The porthyrias and disorders of haem synthesis
The haemoglobulinopathies
Immunology for clinical biochemists
Metabolic bone disease
Biochemical aspects of articular disease
Muscle disease
Investigation of cerebrospinal fluid
Biochemical aspects of psychiatric disorders
Biochemical aspects of neurological disease
Biochemical aspects of mental retardation
Lipid metabolism, hyper- and hypo-lipidaemias
The clinical biochemistry of the cardiovascular system
Therapeutic drug monitoring. Poisoning
Metabolic effects of tumours
Tumour markers
Molecular clinical biochemistry
Free radicals