Glioblastoma - Edition 1 - By Steven Brem, MD and Kalil G. Abdullah, MD Elsevier Educate

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Glioblastoma,

Edition 1

By Steven Brem, MD and Kalil G. Abdullah, MD

Publication Date: 29 Sep 2016

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Clinically focused and designed to provide a to-the-point overview, Glioblastoma, by Drs. Steven Brem and Kalil G. Abdullah, brings you up to date with increased understanding, new treatment protocols, and recent advances in the field. Written by contributing specialists who are global experts in their respective areas, this one-stop reference provides neurosurgeons, medical-and-radiation oncologists, neuro-oncologists, neuropathologists, internal medicine physicians, and researchers with a dependable source of information on current treatment options, tumor recurrence, and patient care.

Key Features

Evidence for current treatment options for de novo and recurrent glioblastoma, indications for local and topical therapies, immunotherapy, gene therapy, nanotherapy, small-molecule inhibition, electric tumor treating field stimulation, and antiangiogenic therapies and the role of Avastin.

Recent advances relating to tumor resection, such as stereotactic laser ablation, diffusion tensor imaging, and fluorescent markers.

Prognostic molecular and genetic markers and the impact of gene mutations on survival, as well as controversies relating to pseudo-progression.

Lessons learned from unsuccessful interventions, as well as the most promising aspects of future glioblastoma research and treatment.

Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

About the author

By Steven Brem, MD, Chief, Neurosurgical Oncology, Co-Director, Penn Brain Tumor Center, Professor of Neurosurgery, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania and Kalil G. Abdullah, MD, Neurosurgery Resident, Department of Neurosurgery, The University of Pennsylvania Hospitals, Philadelphia, Pennsylvania

Part I: Disease Origins and Context

The Story of Glioblastoma: History and Modern Correlates

Epidemiology of Glioblastoma and Trends in Glioblastoma Survivorship

The Molecular Pathogenesis of Glioblastoma

Diagnostic, Prognostic, and Predictive Biomarkers for Adult and Pediatric Gliomas in Clinical Practice

Multimodality Targeting of Glioma Cells

Part II: Standards of Medical and Surgical Treatment

Current Standards of Care in Glioblastoma Therapy

Radiographic Detection and Advanced Imaging of Glioblastoma

Principles and Tenets of Radiation Treatment in

Chemotherapeutics and Their Efficacy

Anti-angiogenic Therapy for Glioblastoma

Recurrent Glioblastoma

Principles of Surgical Treatment

Awake Craniotomy for Glioblastoma

Intraoperative Imaging of Glioblastoma

Minimally Invasive Targeted Therapy for Glioblastoma Laser Interstitial Thermal Therapy (LITT)

Local and Topical Treatment of Glioblastoma

Tumor Treating Electric Fields for Glioblastoma

Part III: Scientific Advances, Future Directions, and Socioeconomic Considerations

Brain Plasticity and Reorganization Before, During, and After Glioma Reseaction

Genetically modified T-cell therapy for glioblastoma

Early Detection of Glioblastoma

Health-Related Quality of Life and Neurocognitive Functioning after Glioblastoma Treatment

Socioeconomics and Survival

National and Global Economic Implications of Glioblastoma

Lessons Learned: Clinical Trials and Other Interventions for Glioblastoma

ISBN: 9780323476607

Page Count: 320

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