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Book Details
Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school.
By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine.
Key Features
- Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine
- Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology
- Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology
About the author
Edited by William B. Coleman, Executive Officer, American Society for Investigative Pathology, Rockville, MD, USA and Gregory J. Tsongalis, PhD, HCLD, CC, FNACB, Professor, Vice Chair for Research, and Director of the Laboratory for Clinical Genomics and Advanced Technologies, Department of Pathology and Laboratory Medicine, Dartmouth Hitchcock Health System and the Audrey and Theodor Geisel School of Medicine, Lebanon, NH, USATitle Reviews
"This is a well-illustrated, easy-to-read book perfectly geared toward aspiring and practicing pathologists. With the growing use of high throughput technologies by medical laboratories, clinicians increasingly rely on genomic, epigenomic, transcriptomic, and proteomic data to classify disease, predict patient outcomes, select therapy, and monitor response to treatment. This book illustrates how scientific discoveries have improved our understanding of disease and catalyzed the era of molecular-guided precision medicine. By highlighting landmark collaborative efforts like the Human Genome Project and new technologies on the horizon, it offers both historical and future-oriented perspectives on the rapidly growing field of genomic medicine. Overall, I would highly recommend this comprehensive textbook to those interested in molecular pathology."—Doody Reviews
Praise for the first edition:
"The book is compact, easy to follow, filled with useful tables and figures and deserves reading by students and professionals interested in the molecular basis of disease."—Howard Reisner PhD, Professor of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, North Carolina, USA
"Finally, a book that captures the real world environment of molecular diagnosis and pathology…is available in Essential Concepts in Molecular Pathology! —Rodney E. Rohde, MS, SV, SM, MP (ASCP), Associate Professor, Texas State University-San Marcos, Clinical Laboratory Science, San Marcos, TX, USA
9780123744197; 9780123706072; 9780123813619





























